Robert Rosen Guide, Meaning , Facts, Information and Description
Robert Rosen (June 27, 1934, Brooklyn, New York - December 28, 1998, Rochester, New York) was an American theoretical biologist and, later in life, a Professor of Biophysics at Dalhousie University until he retired. His main interest was developing a specific definition of complexity and an ensuing theoretical framework, now called "Rosennean Complexity". His main focus was the question: "what is life" ("why are organisms alive?")Another major theme in the work of Robert Rosen was the clarification of the notion of the scientific model. In fact, he maintained that modelling be the essence of science. His book Anticipatory Systems is mainly concerned with what he termed the modelling relationship.
In biology he is known by some for a class of relational cell models called (M,R)-systems that he devised. In these systems he tried to capture the minimal organization a material system would have to manifest to justify calling it a cell. However, Rosen's work proposes a methodology he terms "relational biology" (a term he borrows from Nicolas Rashevsky). Rosen’s "relational biology" maintains that organisms have a distinct quality called "organization" not captured by the language of differential equations but using category theory (a mathematical theory that deals with abstract structures). This study, Rosen says, must be independent from which constitutes a living system.
He goes very far in this direction claiming that "when studying an organized material system, throw away the matter and keep the underlying organization". Relational biology concludes that: (a) "organization" is "that attribute of a natural system which codes into the form of an abstract block diagram” where "abstract block diagram" means a set of arrows and points, (b) physics is unable to capture life essence due the use of a mathematical formalism which is unable to express functions (a teleological notion introduced by Rosen as the behavioral difference between an organism with a "heterogonous state" and one without it). The notion that life can be described as correspondence between some kind of ideal form independent of observable entities (organization) and an abstraction (a mathematical structure) is remarkably similar to Platonism.
Rosen also rejects some aspects of mainstream interpretations of biochemistry and biology. He objects the idea that the functional role of a protein can be investigated purely using the sequence of amino acids, due to intrinsic syntactic limitations of the habitual language of chemistry (graphs of atoms and molecules). Based on this thesis, Rosen says that is impossible to find either an algorithm that can calculate the three-dimensional conformation of a protein directly or the active site of it. "If phenotype is chemistry, as mandated by the sequence hypotheses", he says, "that chemistry is not the familiar contemporary chemistry we find in books". In the case of biology, Rosen maintains that "Darwinian evolution" doesn’t provide any kind of causality or entailment, and without them, "turn evolution, and hence biology, into a collection of pure historical chronicles, like tables of random numbers, or stock exchange quotations". He maintains that the denial of "evolutionary entailments" represents an “excuse itself from science through its absolute denial”. The proposed solution for this problem is embracing entailment in evolution, citing the works of Ernest Haeckel and his idea of “ontogeny recapitulates phylogeny”, René Thom’s Catastrophe Theory and D’Arcy Thompson’s On Growth and Form.
Questions about Rosen's mathematical underpinnings of "relational biology" have been raised in a paper authored by Christopher Landauer and Kirstie L. Bellman which claims that that some of the mathematical "proofs" used by Rosen are dubious. Moreover, the idea that it is possible to establish a correspondence relation between languages and ideal or abstract entities different but related to physical objects has been repudiated in a broad sense from disciplines like linguistics and philosophy of language.
All quotes are from Life Itself: A Comprehensive Inquiry into the Nature, Origin, and Fabrication of Life.
See also: autopoiesis
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