Details, Explanation and Meaning About Rhabdomyolysis

Rhabdomyolysis Guide, Meaning , Facts, Information and Description

Rhabdomyolysis is the breakdown of skeletal muscle due to injury. The injury can be from physical damage to the muscle, but significant cases of rhabdomyolysis are more commonly due to high fever or hyperthermia, metabolic disorders, excessive exertion, flow of electric current through the body or anoxia of the muscle (e.g. Bywaters' crush syndrom or tourniquet left several hours). It has been reported as an extremely rare side-effect of certain classes of medication, notably the statins.

Severe cases of rhabdomyolysis often result in myoglobinuria, a condition where the myoglobin from muscle breakdown spills into the urine, making it "tea colored". This condition can cause serious kidney damage in severe cases. The injured muscle also leaks potassium, leading to hyperkalemia, which may cause fatal disruptions in heart rhythm.

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