Muscle relaxant Guide, Meaning , Facts, Information and Description

In medicine, a muscle relaxant is a drug that causes skeletal muscle contraction to cease. Muscle relaxants are used to facilitate surgery, to enable tracheal intubation and to facilitate mechanical ventilation.

Muscles relaxants typically work by blocking the effect of acetylcholine (ACh) at the neuromuscular junction.

Table of contents

1 Receptor blockers 2 Other mechanisms 3 Central acting muscle relaxants 4 Acting on smooth muscle 5 See also

Receptor blockers

Substances that compete with ACh, for the receptors on a muscle cell can be either depolarising, or non-depolarising.

Depolarising muscles relaxants activate the muscle briefly, before blocking it.

• Succinylcholine (BE) or Suxamethonium (AE)

Non-depolarising relaxants block the ACh receptors without activating them.

• Curare
• Atracurium and Cisatracurium
• Vecuronium
• Rocuronium
• Mivacurium
• Curare-based molecules, e.g. turbocuranine, pancuronium bromide.

Other mechanisms

Botulinum toxin, marketed as Botox for facial wrinkle removal, works by stopping the release of ACh from the presynaptic neuron.

Central acting muscle relaxants

• Benzodiazepines

Acting on smooth muscle

• Amyl nitrite

See also

• Paralysis

This is an Article on Muscle relaxant. Page Contains Information, Facts Details or Explanation Guide About Muscle relaxant

	Web www.E-paranoids.com