Malate dehydrogenase Guide, Meaning , Facts, Information and Description
Malate Dehydrogenase
Malate dehydrogenase is an enzyme, which has several forms. These isoenzymes are listed below:
Variants
(1) GO:0016615 malate dehydrogenase
Def: The catalysis of the reversible convertion of pyruvate or oxaloacetate to malate using NAD or NADPH.
(2) GO:0008924 malate dehydrogenase (acceptor)
Def: none
(3) GO:0030060 malate dehydrogenase 1 (Most commonly mentioned in text books)
Def: The catalysis of the interconversion of malate and NAD to/from oxaloacetate and NADH.
The enzyme combines with nicotinamide adenine dinucleotide to convert L-malate to oxaloacetate.
L-Malate + NAD+ ------> Oxaloacetate + NADH + H+
(4) GO:0004471 malate dehydrogenase (decarboxylating)
Def: Catalysis of the reaction between malate and NAD to produce pyruvate and NADH.
(5) GO:0016619 malate dehydrogenase (oxaloacetate decarboxylating)
Def: Catalysis of the reversible reaction of malate and NAD to pyruvate
and NADH.
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